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Diphenhydramine (Benadryl, etc.) Dosage Table

Child's weight (pounds) 20-24 25-37 38-49 50-99 100+ lbs
Liquid 12.5mg/ 1 teaspoon (tsp) ¾ 1 2 -- tsp
Liquid 12.5 mg/ 5 mililiters (ml) 4 5 7.5 10 -- ml
Chewable 12.5 mg -- 1 2 4 tablets
Tablets 25 mg -- ½ ½ 1 2 tablets
Capsules 25 mg --  -- -- 1 2 caps

Indications: Treatment of allergic reactions, nasal allergies, hives and itching.


Table Notes:

  • AGE LIMITS: For allergies, don't use under 1 year of age (Reason: it's a sedative). For colds, not recommended at any age (Reason: no proven benefits) and should be avoided if under 4 years old. Avoid multi-ingredient products in children under 6 years of age (Reason: FDA recommendations 10/2008).

  • DOSAGE: Determine by finding child's weight in the top row of the dosage table

  • MEASURING the DOSAGE: Syringes and droppers are more accurate than teaspoons. If possible, use the syringe or dropper that comes with the medication. If you use a teaspoon, it should be a measuring spoon. Regular spoons are not reliable. Also, remember that 1 level teaspoon equals 5 ml and that ½ teaspoon equals 2.5 ml.

  • FREQUENCY: Repeat every 6 hours as needed

  • ADULT DOSAGE: 50 mg

  • CHILDREN’S BENADRYL FASTMELTS: Each fastmelt tablet contains the equivalent of 12.5 mg of Diphenhydramine HCL and dosed the same as chewable tablets

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Disclaimer: This information is not intended to be a substitute for professional medical advice. It is provided for educational purposes only. You assume full responsibility for how you choose to use this information. For more information, click here.

Copyright: Copyright 1994-2012 Barton D. Schmitt, M.D.
Author and Senior Reviewer: Barton D. Schmitt, M.D.
Last Revised: 8/16/2011
Content Set: Pediatric HouseCalls Symptom Checker
Version Year: 2012

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