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Diphenhydramine Dosage Table (eg, Benadryl) (Antihistamine)

Child's Weight (pounds) 20-24 25-37  38-49  50-99  100+   lbs 
 Liquid 12.5 mg ¾​ 1 1 ½ --  tsp 
 Liquid 12.5 mg/5 milliliters (mL) 4 5 7.5 10 -- mL
 Chewable 12.5 mg​​ -- 1 1 ½ 2 4 tablets
 Tablets 25 mg -- ½​ ½ 1 2 tablets
 Capsules 25 mg -- -- -- 1 2 caps

​Indications: Treatment of allergic reactions, nasal allergies, hives and itching.​

Table Notes:

  • AGE LIMITS: Avoid diphenhydramine under 6 years of age unless instructed by healthcare provider. Non-sedating alternatives (eg, loratadine, cetirizine, fexofenadine) are available over-the-counter and are safer for young children.
  • DOSAGE: Determine by finding child's weight in the top row of the dosage table
  • MEASURING the DOSAGE: Syringes and droppers are more accurate than teaspoons. If possible, use the syringe or dropper that comes with the medication. If you use a teaspoon, it should be a measuring spoon. Regular spoons are not reliable. Also, remember that 1 level teaspoon equals 5 mL and that ½ a teaspoon equals 2.5 mL.
  • FREQUENCY: Repeat every 6 hours as needed
  • ADULT DOSAGE: 50 mg
  • CHILDREN’S BENADRYL FASTMELTS: Each fastmelt tablet contains the equivalent of 12.5 mg of Diphenhydramine HCL and dosed the same as chewable tablets

Last Updated
7/13/2015
Source
Adapted from My Child Is Sick! Expert Advice for Managing Common Illnesses and Injuries (Copyright © 2011 Barton D. Schmitt, MD, FAAP)
The information contained on this Web site should not be used as a substitute for the medical care and advice of your pediatrician. There may be variations in treatment that your pediatrician may recommend based on individual facts and circumstances.
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